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Yes, a loading phase of several weeks with consistent administration is a standard part of most research protocols

PLoS One 8 , e53419 (2013)

Indeed, small studies have demonstrated that SGLT2 inhibitors can be utilized safely and efficaciously in patients with lupus nephritis, though with fewer studies on GLP1-RA

Sarcopenic obesity, pathogenesis, and treatment with a focus on exercise and protein intake

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