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Moreover, to the best of my knowledge, not a single one of our patients has gone on to develop physiologic or psychologic dependence to ketamine after completing our protocol. However, experts remain alert about any potential for abuse

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Cellulose 26:597615 Tsubota K, Pflugfelder SC, Liu Z, Baudouin C, Kim HM, Messmer EM, Kruse F, Liang L, Carreno-Galeano JT, Rolando M (2020) Defining dry eye from a clinical perspective

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Polymorphisms in CYP1A1, CYP1A2, CYP2C8, CYP2E1, CYP2J2, and CYP3A4 are generally less predictive, but data show that predictive variants exist [14]