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Dwyer T, Whelan D, Shah PS, Ajrawat P, Hoit G, Chahal J

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Notably, while total FOXO4 protein levels remained consistent between young and elderly men, a striking age-dependent shift in its subcellular localization was observed: FOXO4 predominantly resided in the cytoplasm in young Leydig cells but translocated to the nucleus in aged cells

Again, because the patients first two TPE sessions were interrupted due to going to the bathroom, we could remove only 1300 cm 3 rather than 2600 cm 3 of plasma