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Co-primary endpoints were percent change in body weight and the proportion achieving 5% weight loss

Curcumin can not only reduce the production of uric acid by inhibiting the activity of XO, alleviating the symptoms of hyperuricemia and gout to a certain extent [443, 444], but also inhibit the activity of inducible nitric oxide synthase, reducing the production of NO [445, 446]

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Improvement of Overall Survival in Stage IV Melanoma Patients During 20112014: Analysis of Real-World Data in 441 Patients of the German Central Malignant Melanoma Registry (CMMR)