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For example, individuals with heart, kidney, or thyroid problems, cancer, or an auto-immune disease may experience complications with this medication and should consult their doctor first

Additionally, studies have reported potential mild, transient increases in serum cortisol levels, particularly at higher doses

Yesclinical evidence supports long-term GLP-1 therapy for weight maintenance, similar to treating chronic conditions

A meta-analysis examining the effect of GFD on BMI revealed that in spite of having a lower BMI than controls at baseline, patients with CeD had a significant increase in their BMI after starting GFD as compared to controls at last follow-up, and that about 9% of the population changed to a higher BMI category after starting GFD [15]