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This article summarises the position reached with the GLP-1 RAs and reviews the developing field of unimolecular co-agonists that act not only on the GLP-1 receptor, but on other receptors, notably glucose-dependent insulotropic polypeptide (GIP) and glucagon receptors, with the aim of further improving glycaemic control and weight reduction

Mounjaro is approved for the treatment of type 2 diabetes

There was always the option of bariatric surgery, but the side effects were daunting, and some patients managed to circumvent the appetite-limiting effects of stomach-shrinking, regaining much of their initial weight

approximately 62.22% of the patients had a compliance 80%