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NNMT sits at high levels in fat tissue, in many cancer cells and in tissue under metabolic stress, where it acts as a metabolic sink: it consumes NAD+, the coenzyme that powers energy production and cell repair, and S-adenosylmethionine (SAM), the cells main methyl-group donor

Some practitioners in the peptide community do recommend stacking AOD 9604 with GLP-1 agonists, particularly for patients who want to maximize fat loss while minimizing muscle loss

It doesn't create it from nothing

Upon receiving the medication, it should be stored in a refrigerator at 36F to 46F (2C to 8C)

By inhibiting NNMT and preserving NAD, 5-Amino-1MQ triggers a metabolic shift toward greater energy expenditure