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We observed lower levels of M1 glutamate labeling in skeletal muscle of BCATi-treated Mmut p.L690Ins/p.L690Ins mice compared with untreated Mmut p.L690Ins/p.L690Ins and wild-type mice (Supplemental Figure 6B), accompanied by reduced labeling of M1 leucine in skeletal muscle and isoleucine in both liver and skeletal muscle (Supplemental Figure 6C)

This GSH loss is uncorrelated to altered activities of biosynthetic enzyme and not accompanied by an increase in GSSG levels [61]

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Cerebrolysin is supplied as a sterile solution in 1ml, 5ml, 10ml, or 30ml ampules stored at 1525C

Both have a place, but they are not interchangeable, and neither is a substitute for addressing an underlying medical cause when one exists