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Patients with a history of liver disease, pancreatitis, or alcohol use disorder should consult their healthcare provider before consuming any alcohol while taking semaglutide

In regular situations, the HPA axis monitors and modulates immune regulation through numerous hormones, such as glucocorticoids [14-18]

In the active-controlled trials, semaglutide 14 mg demonstrated greater reductions in body weight compared to sitagliptin and liraglutide at 26 weeks, with the exception empagliflozin in PIONEER 2 where no statistically significant difference was observed

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