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Sleep and circadian alignment stabilize metabolic and redox rhythms that gate ROS detoxification and macromolecular repair, improving resilience to daytime oxidative challenges and environmental hygienelimiting UV/photosensitization in exposed tissues and managing metal exposures that expand the labile iron poolcurbs non-enzymatic ROS generation and Fenton chemistry at their source (Davinelli et al

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10.1038/s41575-019-0258-z 65 LiaoC.SeebeckF