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GLP-1RAs and SGLT2is act through distinct and complementary mechanisms of action to exert glycemic control and cardiovascular benefits [4, 9]

However, there was no significant change in liver stiffness

Oral Administration: Unlike other GLP-1 analogues that require weekly injections, Rybelsus can be taken orally, which may appeal to patients who prefer oral medications over injections

Check for air bubbles and expel them if necessary to ensure an accurate measurement

These studies suggest that GLP-1 may mediate cholesterol outflow in hepatocytes through the LXR-ABCA1 pathway, consequently avoiding large amounts of cholesterol accumulation in cells