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Alpha-synucleinmediated DNA damage, STING activation, and neuroinflammation in Parkinsons disease

The GST Mu 1 ( GSTM1 ) rs1056806 [C/T], GST theta 1 ( GSTT1 ) rs17856199 [A/C], GST Pi 1 ( GSTP1 ) rs1695 [A/G], and microsomal GST3 ( mGST3 ) rs2065942 [C/T] variants of this family can impair the GSTs catalytic activities and are studied in multiple diseases, including obesity and related comorbidities [16,27]

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