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The country has over 100 million people living with diabetes the second-highest count globally and faces a growing obesity problem driven by urbanising diets and sedentary lifestyles

Feary JR, Rodrigues LC, Smith CJ, Hubbard RB, Gibson JE

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In clinical trials, 100% of healthy volunteers experienced this chromaturia with administration of 5g hydroxocobalamin with other common effects including erythema, rash (predominantly acneiform appearance) and increased blood pressure

Data from the STEPUP trials showed an increased incidence of dysaesthesia with the 7.2mg dose which largely precluded without need for treatment