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These drugs fall within two categories: human GLP-1 backbone agents (that is, albiglutide, dulaglutide, liraglutide and semaglutide) and exendin-4 backbone agents (that is, exenatide, lixisenatide and tirzepatidethe latter activating both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors) 1

Initial evaluation includes a detailed medical history, physical examination, laboratory testing, and body composition analysis

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the transdermal patch may contain from 0.5- 200 mg of copper tripeptide, preferably from 1- 100, 1-50 and most preferably from 1- 20 mg of copper tripeptide