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The MHRA guidance on the supply of unlicensed medicines (specials) is the controlling regulatory document: an unlicensed product may be supplied only to meet the special clinical needs of an individual patient that a licensed equivalent cannot meet, and the prescriber takes full responsibility for that decision

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(4) O V Korkushko, B A Lapin, N D Goncharova, V Kh Khavinson, et al (2007) Normalizing effect of the pineal gland peptides on the daily melatonin rhythm in old monkeys and elderly people Adv Gerontol, 2007, Volume 20 (Issue 1), Pages 74-85