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If you're planning pregnancy, FDA guidance recommends discontinuing semaglutide approximately 2 months before a planned pregnancy and tirzepatide about 1 month before conception due to potential fetal risks

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Semaglutide mimics this natural process, making sure insulin is released when needed and slowing stomach emptying to prevent sugar spikes after meals

Adam Gilden, MD, MSCE Medical Reviewer Adam Gilden, MD, MSCE, is an associate director of the Obesity Medicine Fellowship at University of Colorado School of Medicine and associate director of the Colorado University Me