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293 In obese mice, there is a marked increase in VEGF, and mammalian target of rapamycin (mTOR), oxidative stress, and ferroptosis within primordial follicles

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Sustained inhibition could have tissue-specific effects that short animal experiments do not fully capture

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Participants receiving 1 mg per day of AOD 9604 lost approximately 2.6 kg compared to 0.8 kg in the placebo group