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Detailed results are provided in Figures S6S8 of the supplementary file

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However, given the large sample size of over 6,000 participants and balancing of factors such as age, sex, etc., these results do provide a valid divergence from other studies, and require more research in future studies

On the other hand, chronic daily administration of THC suppresses weight gain, fat mass gain, and caloric intake in diet-induced, obese rats 20 , and epidemiological data indicate an association between chronic cannabis use and decreased prevalence of obesity and diabetes 21,22,23,24,25,26

To our knowledge this is the most extensive overlap described of a Class B GPCR antibody and peptide agonist