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You may want to add additional magnesium and potassium if you experience increased sweating from the thermogenic effect, as mineral losses through perspiration increase with higher energy expenditure

NICE guidance and manufacturer recommendations emphasise this stepwise escalation to improve tolerability

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The FDA has approved these medications for use in patients with type 2 diabetes and for weight loss in individuals meeting certain criteria, such as BMI and weight-related conditions

However, the effects on the gastrointestinal system are widespread