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Contact your healthcare provider if you experience weight regain of approximately 3-5% of your body weight within a few weeks, return of obesity-related complications such as uncontrolled blood pressure or worsening diabetes control, severe increase in appetite interfering with daily functioning, or psychological distress related to weight changes
What we do know for certain is that semaglutide stays in the body for multiple weeks even after you stop taking it
Why Starting Low and Going Slow Produces Better Results Beginning at the lowest effective dose reduces the risk of gastrointestinal side effects such as nausea, vomiting, and constipation that can discourage treatment adherence
Understanding these guidelines matters because improper handling can compromise the therapy's intended action, and patients deserve clear, evidence-based information to protect their investment in treatment and maintain accountability with their provider