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Several individual lawsuits have been filed against Novo Nordisk, the manufacturer of Ozempic, alleging that the company failed to warn users about the risks of gastroparesis and severe gastrointestinal side effects

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In the ATTAIN-MAINTAIN trial, orforglipron's profile was "consistent with previous orforglipron Phase 3 studies." The most common adverse events were gastrointestinal-related and were generally mild-to-moderate in severity, which is expected for the GLP-1 class

At M6, mean weight loss was significantly higher in the GLP-1-RA group (12.0% [3.3] vs

Am Heart J 2010;159:612619.e3