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Nonobese women with polycystic ovary syndrome respond better than obese women to treatment with metformin

The ARG1 small molecule inhibitor CB-1158 (Table 1) blocks arginase, attenuates myeloid cellmediated immune escape and tumor growth, and is beneficial to T-cell proliferation (Steggerda et al., 2017)

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Finally, different NAD hydrolase proteins also consume NAD + while converting it into ADP-ribose or its cyclic counterpart