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This includes adults with an initial BMI of 30 kg/m 2 and above, or 27 to 29.9 kg/m 2 with at least one weight-associated comorbidity (e.g hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease, prediabetes or T2DM)

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Baseline micronutrient testing can identify B12, iron, or vitamin D deficiencies common during rapid weight loss, which your doctor can address through supplementation

In a 2023 Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al.), retatrutide produced 22.8% to 24.2% mean weight loss at 48 weeks at the higher doses (8 to 12 mg)

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