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We do not prescribe GH-releasing peptides to patients whose IGF-1 is already in the high-normal range for their age, because stimulating further GH elevation in that context produces diminishing returns and increases the theoretical risk of side effects from GH excess

Its safe for long-term daily use in most adults

Grauslund J, Taha AA, Molander LD, et al

MicroRNA-34a regulation of endothelial senescence

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