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The role of Xanthine oxidoreductase and uric acid in metabolic syndrome

Kadia TM, Js C, Konopleva M, Borthakur G, Pemmaraju N, Daver N, Montalban-Bravo G, Issa G, Naqvi K, Short N, Dinardo C, Bhalla K, Jabbour E, Takahashi K, Sasaki K, Kornblau S, Malla R, Pierce S, Estrov Z, Andreeff M , Garcia-Manero G, Ravandi F, and Kantarjian H

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CJC-1295 with DAC requires additional care to avoid thiol-reactive reagents and alkaline conditions