Grace CS, Mikkola HKA, Dou DR, Calvanese V, Ronn RE, Purton LE., "Protagonist or antagonist
GLP-1 Guidance Why the Quiet Phase Often Signals Success TLDR: All you need to know If youre on GLP-1 and feel like nothing is happening, you may be in the quiet phase a normal period where visible progress slows but internal changes are stabilizing
Oral GLP-1 programs remained minimal until the late 2000s, then began rising meaningfully post-2018with the most visible step-up in the last few years: 10 oral programs in 2022, and 11 each in 2024 and 2025
Comment: Several commenters supported the replacement of the Median Time for Discharged ED Patients and LWBS measures with the Emergency Care Access & Timeliness eCQM because electronic data sources reduce administrative burden and enhance real time data availability
3.3.1 Enhancing mitochondrial biogenesis via gene therapy One concept is to upregulate key mitochondrial regulators in patients own cells
