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Your care team can help you decide whether to adjust your dose , slow your escalation, or explore other options

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Ther Adv Endocrinol Metab (2015) 6:10934

may require vitamin B 12 supplementation renal disease alcoholism hepatic disease chronic cardiopulmonary disease (its associated with tissue hypoxia --biguanides may increase the risk of lactic acidosis) Acarbose (Precose) oligosaccharide analog -- strongly binds to intestinal disaccharidases (e.g