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GHK-Cu GHK-Cu is a copper peptide associated with tissue remodeling and collagen production

Using multiple high-throughput proteomics assays in two independent cohorts of konzo-affected children compared to unrelated individuals (Discovery) or their unaffected sibling (Validation) respectively, we demonstrate that levels of the critical plasma-based antioxidant enzyme Glutathione Peroxidase 3 (GPx3) are significantly reduced in those affected

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20 If attempts to shift expression from inclusion bodies to the soluble fraction fail, insoluble GST fusion proteins sometimes can be purified in the presence of denaturants such as urea, followed by refolding