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And the picture is not one-directional: in a human study of surgical inflammation, circulating GLP-1 roughly doubled, with cortisol among the predictors

Most patients will have normal filling pressure and compliance

Regular monitoring of HbA1c (individualised targets, typically 4853 mmol/mol depending on therapy and hypoglycaemia risk), body weight, and thyroid function allows timely treatment adjustments and helps identify when additional interventions are needed

Taper off the medication over 4 to 8 weeks instead of stopping cold