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American Journal of Physiology - Endocrinology and Metabolism (2024) 14

HolstJJrskovCNielsenOVSchwartzTW

DOI: 10.3390/antiox13020184

While patients in the study achieved meaningful weight loss, individual results varied: The research group earlier documented two primary drivers that contributed to patients stopping their medication: cost or insurance coverage limitations and side effects, with the former being the dominant reason

Half-Life and Steady-State Pharmacokinetics Orforglipron's terminal elimination half-life varies with dose and duration of administration