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Intranasal administration, though less studied with Dihexa specifically, would theoretically provide the most direct CNS delivery with minimal systemic exposurepotentially requiring even less frequent dosing to maintain effective brain tissue concentrations

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BPC-157 Research Foundation Studies by Sikiric and colleagues have demonstrated BPC-157's efficacy across multiple tissue types including tendons, muscles, ligaments, gastrointestinal mucosa, and nervous tissue