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The most common side effects are gastrointestinal: nausea (30-44%), diarrhea (19-30%), constipation (10-24%), and occasional vomiting (9-24%)

Proteins were detected via western blotting with the following antibodies: pSTAT3 1:1000 (D3A7), STAT3 1:1000 (79D7), SHP2 1:1000 (D50F2), pAKTS473 1:1000 (D9E), AKT 1:1000 (C67E7), pERKT202/Y204 1:1000 (D13.14

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