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The necrotic lipid core is covered with a collagen fibre-enriched fibrous cup which is lyzed by activation of matrix metalloproteinases (MMP) in the presence of ROS [189, 190] generating an advanced atheromatous plaque called unstable plaque

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And sev 70 percent of the United States population doesnt have sufficient levels which is, uh, defined by the Endocrine Society as 30 nanograms or 30 nanograms per milliliter or more