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Those health impacts not only affect the patient in the short term but lead to increasingly expensive health care as the underlying health issues go untreated

Martin et al., 2020)

Glossary 2-AG 2-arachidonoylglycerol 5-HT1A 5-hydroxytryptamine receptor 1A (serotonin receptor 1A) AEA anandamide BBB bloodbrain barrier BDNF brain-derived neurotrophic factor BrdU bromodeoxyuridine CB1R cannabinoid receptor 1 CB2R cannabinoid receptor 2 CBD cannabidiol CBP cannabis-based products CNS central nervous system COX-2 cyclooxygenase-2 DCX doublecortin ECS endocannabinoid system FAAH fatty acid amide hydrolase GFAP glial fibrillary acidic protein GSH/GSSG reduced glutathione/oxidized glutathione ratio GSK-3 glycogen synthase kinase 3 beta IFG inflammaging IGF-2 insulin-like growth factor 2 IL-1 interleukin-1 IL-6 interleukin-6 LPS lipopolysaccharide MDMA 3,4-methylenedioxymethamphetamine MWT Morris water maze (test) NF-B nuclear factor kappa-light-chain-enhancer of activated B cells NO nitric oxide NOR novel object recognition (test) Ph

A carefully thought-out diet can greatly increase the benefits of GLP-1 drugs, even though they are effective on their own

A novel transdermal drug delivery system for SIN, based on fatty acid-arginine vesicles ([Arg][Dec]), was also developed to enhance SINs transdermal absorption (160)