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While the timing is similar, some research suggests that tirzepatide may have a slightly different side effect profile due to the GIP component, which may help mitigate some of the nausea for certain individuals

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Pregnancy and breastfeeding lack safety data for injectable formulations, warranting avoidance

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EMPA-KIDNEY Trial (n=6,609) This chronic kidney disease trial showed Jardiance reduced kidney disease progression and cardiovascular death risk, with benefits persisting up to one year after treatment discontinuation