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Although high peripheral exposure may be required to obtain the fractional central exposure necessary to illicit a pharmacologic response, insufficient selectivity between MC1R and MC4R activity can lead to peripheral activation of MC1R (142, 143)

Weight loss injections often require refrigeration and always a sharps container to properly and cleanly dispose of the used needle

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MariTide may bring new breakthrough to obesity treatment

Therapeutics with enhanced efficacy, improved pharmacokinetics (PK) allowing less-frequent dosing and good tolerability remain in high demand to address the unmet medical need of patients with obesity