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(PubMed) Ipamorelin is a growth hormone secretagogue (ghrelin receptor agonist class) designed to stimulate GH release with relative selectivity (less spillover into some other pituitary hormones compared with earlier compounds, based on early pharmacology literature)

When administered into the brain circulation and cerebrospinal fluid of mice, DSIP showed a significant, dose-dependent reduction in pain response in the tail-pinch and hot-plate tests