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GLP-1 receptor agonists are believed to inhibit microglial activation, a key driver of neuroinflammation linked to neurodegenerative disorders, thereby protecting neurons

doi: 10.1159/000180686 45 LahnerE.ContiL.CiconeF.CaprielloS.CazzatoM.CentanniM.et al

An intervention study using a low energy diet for weight reduction in 211 overweight or obese participants revealed significant alterations in the gut microbiome with weight loss