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In addition, FOXO4-related peptide inhibits the interaction of p53 with FOXO4 to promote p53-medicated apoptosis [10], and the HSP90 inhibitor 17-DMAG impacts the anti-apoptotic PI3K/AKT pathway [11]

J Clin Invest, 110:2719 Schith HB, Muceniece R, Larsson M, Mutulis F, Szardenings M, Prusis P, Lindeberg G, Wikberg JE (1997) Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes