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While the L973F-IR shifts the signaling pattern from a more metabolic to a more mitogenic pattern, the effects of L973F-IR on growth in vivo were modest

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The treatment protocols consisted of LC administered at a dose of 2 g/day and LAC at 1 g/day, with intervention durations spanning 12 to 24 weeks across the included trials

GLP-1 signaling affects appetite and reward-related pathways in the brain

Le GHRP-6 activates the GHS-R1a receptor in the arcuate nucleus of the hypothalamus, stimulating the orexigenic pathway (NPY/AgRP) and increasing circulating ghrelin levels