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Oral Supplementation Studies suggest that about 56% of an oral B12 supplement is absorbed, but this is largely dependent on the capacity of intrinsic factor (a glycoprotein released by the stomach that is needed for B12 absorption)

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FIGURE 3 One should also keep in mind that the use of various tools for the analysis of each of the individual structural features of an IDP opens additional ways of getting more reliable information about this fuzzy elephant

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From a pharmacokinetic perspective, studies indicate no evidence that the combination of Vitamins B1, B6, and B12 adversely affects the pharmacokinetics of each individual vitamin