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Childs SJ: Dimethyl sulfone (DMSO2) in the treatment of interstitial cystitis

When GLP-1 medications slow movement through an already-inflamed bowel, the combined effect could theoretically worsen symptoms like abdominal pain, diarrhea, or obstruction risk

This combined effect makes it easier to achieve and maintain a caloric deficit, which is fundamental for weight loss

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But molecules that activate PPARs often have side effects