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Larger Phase 3 studies will provide more robust data on efficacy, long-term safety, and tolerability including a more detailed understanding of adverse effects such as dizziness across broader and more diverse patient populations

clinicians should refer to published subgroup data rather than applying population averages to individual patients

Thus, sacubitril monotherapy was not satisfactory and valsartan is used to block undesirable RAAS activation (168)

Future research should focus on improving study quality, standardizing methodologies, the adoption of a standard outcome measure, and expanding representation to improve our understanding of the efficacy and safety of AOMs in this region

However, multivitamins can also contain other added herbal or botanical ingredients that could affect how your body metabolizes medications