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In phase 2A and 2B, randomized, controlled trials in patients with diabetic gastroparesis, relamorelin improved clinical symptoms and appears to be safe, other than the induction of (typically postprandial) hyperglycemia which is attributable to the acceleration of gastric emptying ( FIGURE 1 FIGURE 2 Motilin Receptor Agonists The most common motilin receptor agonists are the macrolide antibiotics that stimulate gastrointestinal motilin receptors, especially gastric receptors

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Front Microbiol.2015;6:1050