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doi: 10.1111/dom.15113, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 23.Blundell J, Finlayson G, Axelsen M, Flint A, Gibbons C, Kvist T, et al

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Melanin influences the colour of the oral mucosa and provides protection against reactive oxygen species and bacterial-derived enzymes and toxins and acts as a physical barrier to both microorganisms invading the oral epithelium and to other microenvironmental stressors

The ACR (American College of Rheumatology) 20% improvement index response was observed in 39% of the RA-1 group versus 30% of placebo

Open Heart, 9 (1), e001989