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Most guidelines support the use of metformin in people with an eGFR of 30 mL/min/1.73 m 2 or greater (although not at maximum recommended doses) and that there is a growing appreciation of temporarily withholding SGLT-2 inhibitors when patients are unwell or need to fast for a prolonged period of time to prevent the development of euglycaemic diabetic ketoacidosis

The reported free-base molecular weight is approximately 889.01 g/mol

Over-the-counter anti-nausea medications like ginger or sea-bands work for some people, though avoiding medications that slow digestion further is important