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Recently, we reported that not only the acute infectious phase [25] but also Long COVID [26] is characterized by concurrent elevations in depression (depressed mood, feelings of guilt, suicidal ideation, loss of interest), anxiety (anxious mood, tension, fears, anxiety behavior at interview), chronic fatigue and somatic symptoms including autonomic and gastrointestinal (GIS) symptoms, malaise and muscle pain

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4 Devasagayam TP, Boloor KK, Ramsarma T

Moreover, both zinc deficiency and zinc supplementation in THP-1-derived macrophages were observed to enhance M1 polarization, while concurrently suppressing M2 polarization