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Reported side effects have included mild injection site reactions or topical irritation in rare cases

Zhu L-B, Zhang Y-C, Huang H-H, Lin J (2021) Prospects for clinical applications of butyrate-producing bacteria

However, to ensure the quality of supplements, people should also choose those that have undergone independent third-party testing

For example, production of the neurotransmitter, 5-HT/serotonin, was reportedly upregulated in the presence of spore-forming Clostridia species , while germ-free mice displayed lower 5-HT/serotonin levels in their colon and blood as well as reduced intestinal motility (Kashyap et al

Many people who suffer from low energy, fatigue, and headaches turn to B12 supplements, often in the form of daily pills