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In this section, we focused on eryptosis in chronic kidney disease (CKD) and end-stage kidney disease patients (ESRD) treated by peritoneal dialysis (PD) or hemodialysis (HD)

Mechanistically, artemisinin and its derivatives directly target LONP1 in theca-interstitial cells, enhancing its interaction with cytochrome P450 family 11 subfamily A member 1 (CYP11A1) and promoting LONP1-catalyzed degradation of CYP11A1

Also, poly (GR) 80 interacts with mitochondrial ribosomal proteins, inducing mitochondrial dysfunction, in motor neurons differentiated from C9orf72 patient iPSCs, compared to controls (Lopez-Gonzalez et al., 2016)

The great thing about capsules, though, is that theyre designed to break down more easily in your digestive system