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245,246 Hence, GLP-1 activates -cells and promotes somatostatin secretion, forming a multi-layered inhibitory mechanism that effectively reduces glucagon secretion

Research shows that there are over 80 medications currently in development, with at least 25 companies testing GLP-1s

Our guide on foods to eat while on GLP-1 medications provides detailed dietary guidance

Furthermore, while initial clinical studies focused on patients with T2D, the kidney-protective role of GLP-1 receptor agonists has now been extended to individuals without T2D

Phenotypic outcomessuch as improved insulin sensitivity or enhanced thermogenesismay provide more robust translational anchors than circulating peptide levels alone